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Pki Alpha Polyclonal Antibody, 50ul Subcellular Fractions tissue specificity:Highly expressed in brain

SKU: 7030161825

4.1
USD185.00 USD219.00

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Pki Alpha Polyclonal Antibody, 50ul Subcellular Fractions tissue specificity:Highly expressed in brainThe protein encoded by PKIA (protein kinase (cAMP dependent, catalytic) inhibitor alpha) is a member of the cAMP dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported.

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Description

tissue specificity:Highly expressed in brain and liver

KCNIP1 encodes a member of the family of cytosolic voltage-gated potassium (Kv) channel-interacting proteins (KCNIPs)

The protein encoded by this gene is overexpressed in chronic lymphocytic leukemia (CLL) and serves as a good prognostic marker for the disease

Since the encoded protein has typical features of a transcription factor| it is postulated to be a repressor of gene expression

also plays a role in regulating the cell cycle by binding to cyclin-Cdk complexes and modulating their activity

Pki Alpha Polyclonal Antibody, 50ul Subcellular Fractions tissue specificity:Highly expressed in brainThe protein encoded by PKIA (protein kinase (cAMP dependent, catalytic) inhibitor alpha) is a member of the cAMP dependent protein kinase (PKA) inhibitor family. This protein was demonstrated to interact with and inhibit the activities of both C alpha and C beta catalytic subunits of the PKA. Alternatively spliced transcript variants encoding the same protein have been reported.

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