Rat Angiopoietin 2, ANG-2 ELISA Kit, 96T Peptide Modification by hydroxylation of the side

by hydroxylation of the side chain

|Transcriptional activator

Promotes cell proliferation and neurogenesis in undifferentiated neural progenitor cells at the embryonic stage and inhibits differentiation of astrocytes (By similarity)

It belongs to the quinone oxidoreductase subfamily of zinc-containing alcohol dehydrogenase proteins

This protein may form oligomeric complexes with family members

Rat Angiopoietin 2, ANG-2 ELISA Kit, 96T Peptide Modification by hydroxylation of the sideBinds to TEK TIE2, competing for the ANGPT1 binding site, and modulating ANGPT1 signaling. Can induce tyrosine phosphorylation of TEK TIE2 in the absence of ANGPT1. In the absence of angiogenic inducers, such as VEGF, ANGPT2 mediated loosening of cell matrix contacts may induce endothelial cell apoptosis with consequent vascular regression. In concert with VEGF, it may facilitate endothelial cell migration and proliferation, thus serving as a