KPNA6 Rabbit Polyclonal Antibody, 20ul Gene Synthesis They mediate protein-carbohydrate interactions by

They mediate protein-carbohydrate interactions by selectively binding to different sialic acid moieties present on glycolipids and glycoproteins

Members of this family are characterized by an N-terminal regulatory domain comprised of a tandem repeat of cysteine-rich zinc-finger motifs and a pleckstrin domain

The encoded protein has no DNA binding activity and therefore can inhibit the DNA binding and transcriptional activation ability of basic HLH proteins with which it interacts

also have a long N-terminal domain (summary by Pi et al

Three transcript variants encoding different isoforms have been found for this gene

KPNA6 Rabbit Polyclonal Antibody, 20ul Gene Synthesis They mediate protein-carbohydrate interactions byNucleocytoplasmic transport a signal and energy dependent process takes place through nuclear pore complexes embedded in the nuclear envelope. The import of proteins containing a nuclear localization signal (NLS) requires the NLS import receptor a heterodimer of importin alpha and beta subunits also known as karyopherins. Importin alpha binds the NLS containing cargo in the cytoplasm and importin beta docks the complex at the cytoplasmic side of the