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TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters The longest gene product (isoform

SKU: 71044808536

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TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters The longest gene product (isoformThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.

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Description

The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing

exposure to certain environmental pollutants

with highest expression in fetal lung

It may be involved also in the broad control of tissue vascularizat

MBP is a useful affinity tag that can increase the expression level and solubility of the resulting tagged protein

TPH1(Phospho Ser260) Polyclonal Antibody, 100ul Transporters The longest gene product (isoformThis gene encodes a member of the aromatic amino acid hydroxylase family. The encoded protein catalyzes the first and rate limiting step in the biosynthesis of serotonin, an important hormone and neurotransmitter. Mutations in this gene have been associated with an elevated risk for a variety of diseases and disorders, including schizophrenia, somatic anxiety, anger related traits, bipolar disorder, suicidal behavior, addictions, and others.

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