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RUNX1 Monoclonal Antibody, 100ul[BT-MCA1114] ssDNA Synthesis This gene has multiple pseudogenes

SKU: 71075694066

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PLN135.00 PLN168.00

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RUNX1 Monoclonal Antibody, 100ul[BT-MCA1114] ssDNA Synthesis This gene has multiple pseudogenesCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have

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Description

This gene has multiple pseudogenes

Variations in this gene may increase susceptibilty to systemic lupus erythematosus (SLE)

tissue specificity:Expressed at high level in the heart

|The conserved cysteine present in the cysteine-switch motif binds the catalytic zinc ion| thus inhibiting the enzyme

The maximum centrifugal force for 1

RUNX1 Monoclonal Antibody, 100ul[BT-MCA1114] ssDNA Synthesis This gene has multiple pseudogenesCore binding factor (CBF) is a heterodimeric transcription factor that binds to the core element of many enhancers and promoters. The protein encoded by this gene represents the alpha subunit of CBF and is thought to be involved in the development of normal hematopoiesis. Chromosomal translocations involving this gene are well documented and have been associated with several types of leukemia. Three transcript variants encoding different isoforms have

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