TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation The entrapped enzyme remains active

The entrapped enzyme remains active against low molecular weight substrates (activity against high molecular weight substrates is greatly reduced)

amygdala and olfactory bulb and is thought to play an important role in neuronal migration and axonal projection

The gene resides on chromosome 16 in the interval containing the locus for polycystic kidney disease (PKD1)

Several transcript variants encoding different isoforms and non-protein coding transcripts have been found for this gene

tissue specificity:Widely expressed with high levels in heart

TGF beta RI(Phospho Ser165) Polyclonal Antibody, 50ul Cell Proliferation The entrapped enzyme remains activeThe protein encoded by this gene forms a heteromeric complex with type II TGF beta receptors when bound to TGF beta, transducing the TGF beta signal from the cell surface to the cytoplasm. The encoded protein is a serine threonine protein kinase. Mutations in this gene have been associated with Loeys Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene.