NLGNX Rabbit Polyclonal Antibody, 20ul Cell Transfection CBFA2T3 (CBFA2/RUNX1 translocation partner 3)

CBFA2T3 (CBFA2/RUNX1 translocation partner 3) encodes a member of the myeloid translocation gene family which interact with DNA-bound transcription factors and recruit a range of corepressors to facilitate transcriptional repression

The multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors

alternative products:Additional isoforms (AAT-1L and AAT-1S) may exist|Isoform 4 may play a role in spermatogenesis

Fusion of ATF1 and FUS on chromosome 16 or EWSR1 on chromosome 22 induced by translocation generates chimeric proteins in angiomatoid fibrous histiocytoma and clear cell sarcoma

Defects in this gene have also been associated with non-familial structural atrial fibrillation

NLGNX Rabbit Polyclonal Antibody, 20ul Cell Transfection CBFA2T3 (CBFA2/RUNX1 translocation partner 3)This gene encodes a member of the type B carboxylesterase lipase protein family. The encoded protein belongs to a family of neuronal cell surface proteins. Members of this family may act as splice site specific ligands for beta neurexins and may be involved in the formation and remodeling of central nervous system synapses. The encoded protein interacts with discs large homolog 4 (DLG4). Mutations in this gene have been associated with autism and