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IKappaB- Alpha Polyclonal Antibody, 50ul[BT-AP04676] Centrifuges Txk expression is T cell-specific

SKU: 71753374021

4.1
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IKappaB- Alpha Polyclonal Antibody, 50ul[BT-AP04676] Centrifuges Txk expression is T cell-specificNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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Description

Txk expression is T cell-specific

using NADP+ as a cofactor

Involved in 2 distinct lysosomal degradation pathways: acts as a regulator of autophagy and as a regulator of G-protein coupled receptors turnover

thus providing most of the energy required for transport processes in the vacuolar system

Potential poly-A sequence starting in position 409

IKappaB- Alpha Polyclonal Antibody, 50ul[BT-AP04676] Centrifuges Txk expression is T cell-specificNFKBIA encodes a member of the NF kappa B inhibitor family, which contain multiple ankrin repeat domains. The encoded protein interacts with REL dimers to inhibit NF kappa B REL complexes which are involved in inflammatory responses. The encoded protein moves between the cytoplasm and the nucleus via a nuclear localization signal and CRM1 mediated nuclear export. Mutations in this gene have been found in ectodermal dysplasia anhidrotic with T cell

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