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HLAE Polyclonal Antibody, 50ul Sampling Tubes It is widely distributed in

SKU: 71806238549

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HLAE Polyclonal Antibody, 50ul Sampling Tubes It is widely distributed inHLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1

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Description

It is widely distributed in peripheral organs| such as liver and kidney| and is also present in low amounts in the central nervous system

|tissue specificity:Expressed at low levels in several tissues| including brain| kidney| lung| prostate| testis| spinal cord| adrenal gland| and trachea

Can be phosphorylated in vitro by PRKDC/DNA-PK in the presence of Ku and DNA

and alterations in the expression of PAX5 are thought to contribute to neoplastic transformation

Multifunctional epidermal matrix protein

HLAE Polyclonal Antibody, 50ul Sampling Tubes It is widely distributed inHLA E belongs to the HLA class I heavy chain paralogues. This class I molecule is a heterodimer consisting of a heavy chain and a light chain (beta 2 microglobulin). The heavy chain is anchored in the membrane. HLA E binds a restricted subset of peptides derived from the leader peptides of other class I molecules. The heavy chain is approximately 45 kDa and its gene contains 8 exons. Exon one encodes the leader peptide, exons 2 and 3 encode the alpha1

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