MED9 Polyclonal Antibody, 20ul Adeno-associated Virus Packaging DGKD encodes a cytoplasmic enzyme

DGKD encodes a cytoplasmic enzyme that phosphorylates diacylglycerol to produce phosphatidic acid

leading to cell cycle arrest in G1

Couples activation of these receptors and their associated kinases with distal intracellular events such as mobilization of intracellular calcium stores| PKC activation| MAPK activation or cytoskeletal reorganization through the recruitment of PLCG1| GRB2| GRAP2| and other signaling molecules

It is thought that this pathway contributes to Rho-induced reorganization of the actin cytoskeleton

A transcript variant retaining intronic sequence and encoding a shorter isoform has been described

MED9 Polyclonal Antibody, 20ul Adeno-associated Virus Packaging DGKD encodes a cytoplasmic enzymeThe multiprotein Mediator complex is a coactivator required for activation of RNA polymerase II transcription by DNA bound transcription factors. The protein encoded by this gene is thought to be a subunit of the Mediator complex. This gene is located within the Smith Magenis syndrome region on chromosome 17.