Phospho-Stat3 (Y705) mouse Monoclonal Antibody(1E9), 50ul Shakers The product of this gene

The product of this gene is a member of the saposin-like protein (SAPLIP) family and is located in the cytotoxic granules of T cells

supports the notion that it is a candidate gene for neuroblastoma

and mutations in this gene have been associated with pseudohypoaldosteronism type 1 (PHA1)

synthesizes small RNA primers for the Okazaki fragments made during discontinuous DNA replication

Multiple transcription initiation sites have been identified and extensive alternative splicing occurs in the 5' untranslated region

Phospho-Stat3 (Y705) mouse Monoclonal Antibody(1E9), 50ul Shakers The product of this geneThe protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated through phosphorylation in response to various cytokines and growth factors including IFNs, EGF, IL5, IL6, HGF, LIF and