KLK12 Polyclonal Antibody, 20ul Enzymes Expression in specific hematopoietic lineages

Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation

Overexpression of this gene is associated with glioblastoma

It participates in the formation of the Membrane Attack Complex (MAC)

and modulating cell growth

which acts as a biologic mediator in several processes

KLK12 Polyclonal Antibody, 20ul Enzymes Expression in specific hematopoietic lineagesKallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Alternate splicing of this gene results in three transcript variants encoding different isoforms.