CALRL Polyclonal Antibody, 50ul Cell Function Analysis Alternatively spliced transcript variants encoding

Alternatively spliced transcript variants encoding different isoforms have been reported

Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities

and both are required for IL23A signaling

This gene is proposed to function downstream of homeobox C8 to transduce extracellular patterning information during axial skeleton development

and telecanthus (MMCAT) and cone-rod dystrophy in human patients

CALRL Polyclonal Antibody, 50ul Cell Function Analysis Alternatively spliced transcript variants encodingReceptor for calcitonin gene related peptide (CGRP) together with RAMP1 and receptor for adrenomedullin together with RAMP2 or RAMP3 (By similarity). The activity of this receptor is mediated by G proteins which activate adenylyl cyclase.,Belongs to the G protein coupled receptor 2 family.,subunit: Heterodimer of CALCRL and RAMP1, RAMP2 or RAMP3.,tissue specificity: Predominantly expressed in the lung and heart.,