LYAG Rabbit Polyclonal Antibody, 50ul Sampling Tubes The MutL-alpha heterodimer possesses an

The MutL-alpha heterodimer possesses an endonucleolytic activity that is activated following recognition of mismatches and insertion/deletion loops by the MutS-alpha and MutS-beta heterodimers

This gene belongs to the A/B subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs)

The gene product has been identified as a tumor suppressor in gastric (PMID: 21602894

It is located in intracellular vesicles

The encoded protein is a single-pass type I membrane protein and contains 8 immunoglobulin-like C2-type domains

LYAG Rabbit Polyclonal Antibody, 50ul Sampling Tubes The MutL-alpha heterodimer possesses anThis gene encodes lysosomal alpha glucosidase which is essential for the degradation of glycogen to glucose in lysosomes. The encoded preproprotein is proteolytically processed to generate multiple intermediate forms and the mature form of the enzyme. Defects in this gene are the cause of glycogen storage disease II also known as Pompe's disease which is an autosomal recessive disorder with a broad clinical spectrum. Alternative splicing results in