HES3 Polyclonal Antibody, 50ul Liquid Storage Consumables Members of the 'frizzled' gene

Members of the 'frizzled' gene family encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins

and single nucleotide polymorphisms in this gene are associated with blood pressure variation

Two alternatively spliced transcript variants encoding different isoforms are described for this gene

and appears to determine the specificity of the protein's homophilic cell adhesion activity

A similar protein in yeast functions as a methylesterase| converting methylated diphthine to diphthine| which can then undergo amidation to produce diphthamide

HES3 Polyclonal Antibody, 50ul Liquid Storage Consumables Members of the 'frizzled' geneHas a particular type of basic domain (presence of a helix interrupting proline) that binds to the N box (CACNAG), rather than the canonical E box (CANNTG).,The C terminal WRPW motif is a transcriptional repression domain necessary for the interaction with Groucho TLE family members, transcriptional corepressors recruited to specific target DNA by Hairy related proteins.,Transcriptional repressor of genes that require a bHLH protein for their