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Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) TAF1A (TATA-box binding protein associated

SKU: 7407237736

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Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) TAF1A (TATA-box binding protein associatedSerine threonine protein kinase involved in transcription regulation, p53 TP53 mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1 Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53 TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53

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Description

TAF1A (TATA-box binding protein associated factor

Mutations in this gene result in persistent Mullerian duct syndrome

The encoded protein contains 17 leucine-rich repeats and one PDZ domain

EDN1 encodes a preproprotein that is proteolytically processed to generate a secreted peptide that belongs to the endothelin/sarafotoxin family

or a heterodimer with the related protein hepatocyte nuclear factor 1-alpha

Human Homeodomain-interacting Protein Kinase 2, HIPK2 ELISA Kit, 96T Enzyme-Linked Immunosorbent Assay (ELISA) TAF1A (TATA-box binding protein associatedSerine threonine protein kinase involved in transcription regulation, p53 TP53 mediated cellular apoptosis and regulation of the cell cycle. Acts as a corepressor of several transcription factors, including SMAD1 and POU4F1 Brn3a and probably NK homeodomain transcription factors. Phosphorylates PDX1, ATF1, PML, p53 TP53, CREB1, CTBP1, CBX4, RUNX1, EP300, CTNNB1, HMGA1 and ZBTB4. Inhibits cell growth and promotes apoptosis through the activation of p53

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