AVR2B Polyclonal Antibody, 20ul Immunology The encoded protein is a

The encoded protein is a large subunit of adaptor protein complex-4

Mutations in this gene are associated with gingival fibromatosis 1 and Noonan syndrome type 4

It may also negatively regulate cell proliferation through interaction with the C-terminal region of the adenomatosis polyposis coli tumor suppressor protein

and this coupling activates a phosphatidylinositol-calcium second messenger system

LTE4 and 12-HETE

AVR2B Polyclonal Antibody, 20ul Immunology The encoded protein is aActivins are dimeric growth and differentiation factors which belong to the transforming growth factor beta (TGF beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand binding extracellular domain with cysteine rich