Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes disease:Defects in CDKN2A are a

disease:Defects in CDKN2A are a cause of Li-Fraumeni syndrome (LFS)

This gene has been linked to non-small cell lung cancer

Contains 1 Ig-like C1-type (immunoglobulin-like) domain

Other studies indicate that H2O2 is also essential for growth-factor mediated signal transduction

It is an important component of cAMP-mediated signal transduction during the spermatogenetic cycle

Ku-70 Polyclonal Antibody, 50ul[BT-AP04893] Serum & Sample Tubes disease:Defects in CDKN2A are aThe p70 p80 autoantigen is a nuclear complex consisting of two subunits with molecular masses of approximately 70 and 80 kDa. The complex functions as a single stranded DNA dependent ATP dependent helicase. The complex may be involved in the repair of nonhomologous DNA ends such as that required for double strand break repair, transposition, and V(D)J recombination. High levels of autoantibodies to p70 and p80 have been found in some patients with