OTX1 Rabbit Polyclonal Antibody, 100ul Immunology FLI1 encodes friend leukemia integration

FLI1 encodes friend leukemia integration 1 transcription factor containing an ETS DNA-binding domain

A mutation in this gene was associated with microphthalmia| syndromic 13

which is controlled by the regulatory subunits D-type cyclins and CDK inhibitor p16(INK4a)

The protein associates with the U3 small nucleolar ribonucleoprotein 60-80S complexes and may be involved in pre-rRNA processing

and regulate the activity of numerous protein kinases of the JNK signaling pathway

OTX1 Rabbit Polyclonal Antibody, 100ul Immunology FLI1 encodes friend leukemia integrationThis gene encodes a member of the bicoid sub family of homeodomain containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mouse is required for proper brain and sensory organ development and can cause epilepsy. Alternative splicing results in multiple transcript variants.