SLC4A8/10 Polyclonal Antibody, 50ul In vitro Assessment Mutations in this gene cause

Mutations in this gene cause familial hypertrophic cardiomyopathy and atrial septal defect 3

and trigger apoptosis of various tumor cells

Two transcript variants encoding the same protein but differing in the 5' UTR

Expertly designed and versatile

This gene is located in the cystatin locus and encodes a secreted protein that may play a role in hematopoietic differentiation or inflammation

SLC4A8/10 Polyclonal Antibody, 50ul In vitro Assessment Mutations in this gene causeSLC4A10 (solute carrier family 4 member 10) belongs to a small family of sodium coupled bicarbonate transporters (NCBTs) that regulate the intracellular pH of neurons, the secretion of bicarbonate ions across the choroid plexus, and the pH of the brain extracellular fluid. The protein encoded by SLC4A10 was initially identified as a sodium driven chloride bicarbonate exchanger (NCBE) though there is now evidence that its sodium bicarbonate cotransport