Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller Demethylates both di- and trimethylated

Demethylates both di- and trimethylated H3 'Lys-9' residue

PTM:Proteolytically cleaved by caspase-8 during TNF-induced apoptosis

Adjustable vacuum level with indicator light is designed for various applications

It has now been found that this gene is involved in the regulation of many NR and non-NR activities| including metabolism| adipogenesis and chromatin organization

This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19

Rb(Phospho Thr826) Polyclonal Antibody, 50ul Pipette Controller Demethylates both di- and trimethylatedThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.