NGAP Polyclonal Antibody, 20ul Biomatrix Various mutations of PMP22 are

Various mutations of PMP22 are causes of Charcot-Marie-Tooth disease Type IA

this protein contains a C-terminal CAAX motif that is characteristic of many RAS superfamily members but which is not found in YPT1 and the majority of RAB proteins

HM74B is highly expressed in adipocytes

such as systemic lupus erythematosus

The protein encoded by this gene belongs to a subfamily of tyrosine kinase receptors with homology to Dictyostelium discoideum protein discoidin I in their extracellular domain| and that are activated by various types of collagen

NGAP Polyclonal Antibody, 20ul Biomatrix Various mutations of PMP22 areThis gene encodes a protein that contains the GAP related domain (GRD) a characteristic domain of GTPase activating proteins (GAPs). GAPs function as activators of Ras superfamily of small GTPases. The protein encoded by this gene is able to complement the defective RasGAP function in a yeast system. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.