Vimentin Polyclonal Antibody, 50ul[BT-AP09530] Palm Micro Centrifuges Members of the IRF family

Members of the IRF family are characterized by a conserved N-terminal DNA-binding domain containing tryptophan (W) repeats

Mutations in this gene result in alpha-2-plasmin inhibitor deficiency| which is characterized by severe hemorrhagic diathesis

tissue specificity:Expressed in lymphocyte-rich tissues

Defects in this gene may result in apolipoprotein A-II deficiency or hypercholesterolemia

An elevated level of serum urate| hyperuricemia| is associated with increased incidences of gout| and mutations in this gene cause renal hypouricemia type 1

Vimentin Polyclonal Antibody, 50ul[BT-AP09530] Palm Micro Centrifuges Members of the IRF familyVIM (vimentin) encodes a member of the intermediate filament family. Intermediate filamentents, along with microtubules and actin microfilaments, make up the cytoskeleton. The protein encoded by VIM is responsible for maintaining cell shape, integrity of the cytoplasm, and stabilizing cytoskeletal interactions. It is also involved in the immune response, and controls the transport of low density lipoprotein (LDL) derived cholesterol from a lysosome to