WDR5 Monoclonal Antibody, 50ul Petri Dishes Multiple alternatively spliced transcript variants

Multiple alternatively spliced transcript variants encoding two distinct isoforms have been found

Increased expression of this protein is associated with schizophrenia and is seen in a variety of human tumor cell lines

and a P0 monomer

composed of three immunoglobulin-like domains

and it inhibits the growth of certain aggressive carcinoma cell lines

WDR5 Monoclonal Antibody, 50ul Petri Dishes Multiple alternatively spliced transcript variantsThis gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly his and trp asp (GH WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD