TRFM Polyclonal Antibody, 100ul Antibody Humanization Mutations in this gene are

Mutations in this gene are associated with progressive epilepsy with mental retardation (EMPR)

The encoded protein forms a complex with the Fc receptor gamma-chain that initiates the platelet activation signaling cascade upon collagen binding

shaker-related subfamily

Studies in mice suggest that the encoded protein may act as a protein receptor for botulinum neurotoxin E in neurons

as well as in genotoxic stress response

TRFM Polyclonal Antibody, 100ul Antibody Humanization Mutations in this gene areThe protein encoded by this gene is a cell surface glycoprotein found on melanoma cells. The protein shares sequence similarity and iron binding properties with members of the transferrin superfamily. The importance of the iron binding function has not yet been identified. This gene resides in the same region of chromosome 3 as members of the transferrin superfamily. Alternative splicing results in two transcript variants.