Insulin Polyclonal Antibody, 50ul[BT-AP10405] Centrifuge Tube (Bottle) Mutations in this gene have

Mutations in this gene have been associated with Sertoli cell-only syndrome and male infertility

EMX2 encodes a homeobox-containing transcription factor that is the homolog to the empty spiracles gene in Drosophila

This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17

which suggests its involvement in a regulated signaling process

This encoded protein is one of two V1 domain A subunit isoforms and is found in all

Insulin Polyclonal Antibody, 50ul[BT-AP10405] Centrifuge Tube (Bottle) Mutations in this gene haveAfter removal of the precursor signal peptide, proinsulin is post translationally cleaved into three peptides: the B chain and A chain peptides, which are covalently linked via two disulfide bonds to form insulin, and C peptide. Binding of insulin to the insulin receptor (INSR) stimulates glucose uptake. A multitude of mutant alleles with phenotypic effects have been identified. There is a read through gene, INS IGF2, which overlaps with this gene at