JAK2 Rabbit Polyclonal Antibody, 50ul ADME It was found to be

It was found to be one of the mitochondrial matrix proteins that are preferentially degraded by the serine protease 15(PRSS15)

notch interaction with its cell-bound ligands(delta

This gene is located in a tail-to-tail configuration with another member of the gene family on the long arm of chromosome 17

The family is characterized by the presence of the DNA-binding T-box domain and is divided into five sub-families based on sequence conservation in this domain

An important paralog of this gene is ZDHHC15

JAK2 Rabbit Polyclonal Antibody, 50ul ADME It was found to beThis gene product is a protein tyrosine kinase involved in a specific subset of cytokine receptor signaling pathways. It has been found to be constituitively associated with the prolactin receptor and is required for responses to gamma interferon. Mice that do not express an active protein for this gene exhibit embryonic lethality associated with the absence of definitive erythropoiesis.