Human Progranulin, GRN ELISA Kit, 5*96T Plates & Dishes Also plays a role in

Also plays a role in apoptosis through its ability to bind in a calcium-independent manner the DNA present at the surface of apoptotic cells and to activate the complement in response to this binding

They play important roles in intracellular vesicle transport and cell division (summary by Venturelli et al

Suppressor of microRNA (miRNA) biogenesis

In the case of the FOS AU-rich element

Plays a role in rapid mRNA degradation by binding to the 5' UTR of target mRNAs and interacting with PNRC2 in a ligand-dependent manner which recruits the RNA helicase UPF1 and the mRNA-decapping enzyme DCP1A

Human Progranulin, GRN ELISA Kit, 5*96T Plates & Dishes Also plays a role in