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Nkx-3.1 Monoclonal Antibody, 100ul Diagnostic Probes & Oligos This gene is the human

SKU: 77653579837

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PLN135.00 PLN168.00

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Nkx-3.1 Monoclonal Antibody, 100ul Diagnostic Probes & Oligos This gene is the humanThis gene encodes a homeobox containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.

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Description

This gene is the human homolog of mouse BMP-2-inducible kinase

HIF-1 thus plays an essential role in embryonic vascularization

The chromosomal rearrangements are the most common genetic alterations in this gene| which result in creation of multiple fusion genes in tumourigenesis| including ALK (chromosome 2)/EML4 (chromosome 2)| ALK/RANBP2 (chromosome 2)| ALK/ATIC (chromosome 2)| ALK/TFG (chromosome 3)| ALK/NPM1 (chromosome 5)| ALK/SQSTM1 (chromosome

a basic arginine-rich region

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Nkx-3.1 Monoclonal Antibody, 100ul Diagnostic Probes & Oligos This gene is the humanThis gene encodes a homeobox containing transcription factor. This transcription factor functions as a negative regulator of epithelial cell growth in prostate tissue. Aberrant expression of this gene is associated with prostate tumor progression. Alternate splicing results in multiple transcript variants of this gene.

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