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PO2F3 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance Each component of the AHP

SKU: 77720832729

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PO2F3 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance Each component of the AHPThis gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene

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Description

Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels

and has been shown to form dimers/oligomers through its leucine-zipper motif

The protein has substantial GAP activity towards several Rho-family GTPases in vitro

This protein is thus a potential drug target for the treatment of muscle atrophy

Some modulators interact directly with the basal complex

PO2F3 Rabbit Polyclonal Antibody, 50ul Cell Culture & Maintenance Each component of the AHPThis gene encodes a member of the POU domain family of transcription factors. POU domain transcription factors bind to a specific octamer DNA motif and regulate cell type specific differentiation pathways. The encoded protein is primarily expressed in the epidermis and plays a critical role in keratinocyte proliferation and differentiation. The encoded protein is also a candidate tumor suppressor protein and aberrant promoter methylation of this gene

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