Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis Alternate splicing of this gene

Alternate splicing of this gene results in several transcript variants encoding different isoforms

This protein plays a role in the formation and maintenance of adult intestinal stem cells during postembryonic development

NANOG plays a central role in regulating self-renewal in pluripotent stem cells and tumor cells

Impaired spindle checkpoint function has been found in many forms of cancer

Dengue virus (DNV)

Tuberin Polyclonal Antibody, 50ul[BT-AP09287] Cell Function Analysis Alternate splicing of this geneMutations in TSC2 lead to tuberous sclerosis complex. Its gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases. The protein associates with hamartin in a cytosolic complex, possibly acting as a chaperone for hamartin. Alternative splicing results in multiple transcript variants encoding different isoforms.