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Phospho-Akt1/3 (Y437/434) Polyclonal Antibody, 20ul Culture Plate Inserts tumor development and inflammation

SKU: 78420909225

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Phospho-Akt1/3 (Y437/434) Polyclonal Antibody, 20ul Culture Plate Inserts tumor development and inflammationThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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Description

tumor development and inflammation

Alternatively spliced transcript variants have been observed for this gene

which is an interacting protein of alpha synuclein in neurons

it is now believed that there is only one type 1 receptor gene in humans

The structural organization of this gene also suggested that it had diverged considerably from the beta chain genes

Phospho-Akt1/3 (Y437/434) Polyclonal Antibody, 20ul Culture Plate Inserts tumor development and inflammationThe serine threonine protein kinase encoded by the AKT1 gene is catalytically inactive in serum starved primary and immortalized fibroblasts. AKT1 and the related AKT2 are activated by platelet derived growth factor. The activation is rapid and specific, and it is abrogated by mutations in the pleckstrin homology domain of AKT1. It was shown that the activation occurs through phosphatidylinositol 3 kinase. In the developing nervous system AKT is a

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