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Raf-1 Polyclonal Antibody, 100ul[BT-AP07627] Fluorescent Staining Multiple alternatively spliced transcript variants

SKU: 78699962339

4.5
PLN108.00 PLN141.00

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Raf-1 Polyclonal Antibody, 100ul[BT-AP07627] Fluorescent Staining Multiple alternatively spliced transcript variantsRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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Description

Multiple alternatively spliced transcript variants have been found for this gene

which contribute to the regulation of surface expression and gating of calcium channels and may also play a role in the regulation of transcription factors and calcium transport

Translocation t(X

CdkL4 (cyclin-dependent kinase-like 4) is a 315 amino acid protein that belongs to the CMGC Ser/Thr protein kinase family and may be involved in cell cycle regulation

Mutations in GATA4 have been associated with cardiac septal defects

Raf-1 Polyclonal Antibody, 100ul[BT-AP07627] Fluorescent Staining Multiple alternatively spliced transcript variantsRAF1 (Raf 1 proto oncogene, serine threonine kinase) is the cellular homolog of viral raf gene (v raf). The encoded protein is a MAP kinase kinase kinase (MAP3K), which functions downstream of the Ras family of membrane associated GTPases to which it binds directly. Once activated, the cellular RAF1 protein can phosphorylate to activate the dual specificity protein kinases MEK1 and MEK2, which in turn phosphorylate to activate the serine threonine

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