PAK Alpha/Beta/Gamma Polyclonal Antibody, 50ul[BT-AP06898] Peripheral Blood Separation Tube and a proline-rich region

and a proline-rich region

a spacer region

are the main components of the nuclear pore complex in eukaryotic cells

Involved in the regulation of structural processes in differentiating and mature neuronal cells

Reductions in the expression of this gene have been associated with Down's syndrome and Alzheimer's disease

PAK Alpha/Beta/Gamma Polyclonal Antibody, 50ul[BT-AP06898] Peripheral Blood Separation Tube and a proline-rich regionPAK1 encodes a family member of serine threonine p21 activating kinases, known as PAK proteins. These proteins are critical effectors that link RhoGTPases to cytoskeleton reorganization and nuclear signaling, and they serve as targets for the small GTP binding proteins Cdc42 and Rac. This specific family member regulates cell motility and morphology. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.