FoxO3A Polyclonal Antibody, 50ul[BT-AP15669] Pipette Holder Several pseudogenes have been associated

Several pseudogenes have been associated with this gene

tissue specificity:Found in cerebellum and frontal cortex

the ubiquinone-mediated oxidation of dihydroorotate to orotate

the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins

The protein may play a role in tumor formation by inhibiting apoptosis and promoting angiogenesis

FoxO3A Polyclonal Antibody, 50ul[BT-AP15669] Pipette Holder Several pseudogenes have been associatedThis gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. This gene likely functions as a trigger for apoptosis through expression of genes necessary for cell death. Translocation of this gene with the MLL gene is associated with secondary acute leukemia. Alternatively spliced transcript variants encoding the same protein have been observed.