HNF-1Beta Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Two transcript variants resulting from

Two transcript variants resulting from alternative splicing have been identified

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which communicates its intracellular signal by inhibition of adenylyl cyclase through Gi

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PKC subfamily

HNF-1Beta Polyclonal Antibody, 50ul Hybridoma Antibody Sequencing Two transcript variants resulting fromHNF1B encodes a member of the homeodomain containing superfamily of transcription factors. Hepatocyte nuclear factor 1 beta binds to DNA as either a homodimer, or a heterodimer with the related protein hepatocyte nuclear factor 1 alpha. The gene has been shown to function in nephron development, and regulates development of the embryonic pancreas. Mutations in this gene result in renal cysts and diabetes syndrome and noninsulin dependent diabetes