Filamin 1 Polyclonal Antibody, 20ul Cell fragmentation and collection Defects in FLNA are a

Defects in FLNA are a cause of several syndromes

and with distal myopathies

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The encoded protein contains sequence and structural similarity to members of the neprilysin (M13) family of zinc endopeptidases

and stable gene expression

Filamin 1 Polyclonal Antibody, 20ul Cell fragmentation and collection Defects in FLNA are aFilamin A encoded by FLNA is an actin binding protein that crosslinks actin filaments and links actin filaments to membrane glycoproteins. Filamin A is involved in remodeling the cytoskeleton to effect changes in cell shape and migration. Filamin A interacts with integrins, transmembrane receptor complexes, and second messengers. Defects in FLNA are a cause of several syndromes, including periventricular nodular heterotopias (PVNH1, PVNH4),