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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03040] Rotator These isoforms exhibit different expression

SKU: 79062934815

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ErbB-3 Polyclonal Antibody, 100ul[BT-AP03040] Rotator These isoforms exhibit different expressionERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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Description

These isoforms exhibit different expression patterns and varying levels of GEF activity

Recruits TFIIH to the initiation complex and stimulates the RNA polymerase II C-terminal domain kinase and DNA-dependent ATPase activities of TFIIH

Family members contain two highly conserved

Defects in SNCA have been implicated in the pathogenesis of Parkinson disease

Mutations in this gene cause corticosterone methyl oxidase deficiency

ErbB-3 Polyclonal Antibody, 100ul[BT-AP03040] Rotator These isoforms exhibit different expressionERBB3 encodes a member of the epidermal growth factor receptor (EGFR) family of receptor tyrosine kinases. This membrane bound protein has a neuregulin binding domain but not an active kinase domain. It therefore can bind this ligand but not convey the signal into the cell through protein phosphorylation. However, it does form heterodimers with other EGF receptor family members which do have kinase activity. Heterodimerization leads to the activation

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