MAN1 Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging Defects in this gene result

Defects in this gene result in premature ovarian failure type 5

It is also found in dentin in much higher quantities than other plasma proteins

Studies of the mouse counterpart also suggest that this protein and its ligand play a role in lymph-node organogenesis and vascular calcification

The encoded protein has been shown to promote neuronal differentiation by deglycination of the Notch receptor

This hormone contracts smooth muscle during parturition and lactation

MAN1 Rabbit Polyclonal Antibody, 50ul Cell Screening and Imaging Defects in this gene resultThis locus encodes a LEM domain containing protein. The encoded protein functions to antagonize transforming growth factor beta signaling at the inner nuclear membrane. Two transcript variants encoding different isoforms have been found for this gene. Mutations in this gene have been associated with osteopoikilosis Buschke Ollendorff syndrome and melorheostosis.