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RARR2 Polyclonal Antibody, 20ul Plates & Dishes This gene is a susceptibility

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RARR2 Polyclonal Antibody, 20ul Plates & Dishes This gene is a susceptibilityThis gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein coupled seven transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine and as an antimicrobial protein with activity against bacteria and fungi.

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Description

This gene is a susceptibility locus for schizophrenia and bipolar disorder

The encoded protein is highly similar to the mouse and rat CK1 delta homologs

Dematin actin binding protein encoded by DMTN is an actin binding and bundling protein that plays a structural role in erythrocytes

Also expressed in certain liver and kidney carcinomas

|PTM:Phosphorylation on Ser-421 and Ser-423 promotes enzymatic activity and interactions with NuRD and SIN3 complexes

RARR2 Polyclonal Antibody, 20ul Plates & Dishes This gene is a susceptibilityThis gene encodes a secreted chemotactic protein that initiates chemotaxis via the ChemR23 G protein coupled seven transmembrane domain ligand. Expression of this gene is upregulated by the synthetic retinoid tazarotene and occurs in a wide variety of tissues. The active protein has several roles, including that as an adipokine and as an antimicrobial protein with activity against bacteria and fungi.

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