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Frizzled-9 Polyclonal Antibody, 100ul[BT-AP03370] Protein Analysis An important paralog of this

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Frizzled-9 Polyclonal Antibody, 100ul[BT-AP03370] Protein Analysis An important paralog of thisMembers of the frizzled gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene (frizzled class receptor 9) is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.

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Description

An important paralog of this gene is RIMKLA

Has a two domain structure: the G-domain binds GTP

The encoded protein stabilizes the ORC and therefore aids in DNA replication

A pseudogene has been identified on chromosome 1

It is thought to promote resistance to UV and 4-hydroxy-2-nonenal-induced oxidative damage in the cornea

Frizzled-9 Polyclonal Antibody, 100ul[BT-AP03370] Protein Analysis An important paralog of thisMembers of the frizzled gene family encode 7 transmembrane domain proteins that are receptors for Wnt signaling proteins. The FZD9 gene (frizzled class receptor 9) is located within the Williams syndrome common deletion region of chromosome 7, and heterozygous deletion of the FZD9 gene may contribute to the Williams syndrome phenotype. FZD9 is expressed predominantly in brain, testis, eye, skeletal muscle, and kidney.

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