Presenilin 2 Rabbit Polyclonal Antibody, 20ul Protein Expression Defects in this gene are

Defects in this gene are a cause of female-specific osteoarthritis (OA) susceptibility

Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I)

GPR15 encodes a G protein-coupled receptor that acts as a chemokine receptor for human immunodeficiency virus type 1 and 2

Multiple cysteine residues are necessary for proper targeting to the plasma membrane

This gene encodes a peptidoglycan recognition protein

Presenilin 2 Rabbit Polyclonal Antibody, 20ul Protein Expression Defects in this gene areAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1 or PSEN2) or the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase an enzyme that cleaves APP. Also