LOXL4 Rabbit Polyclonal Antibody, 100ul Cell Culture Two transcript variants that encode

Two transcript variants that encode different isoforms have been identified for this gene

The protein encoded by this gene belongs to the superfamily of small heat-shock proteins containing a conservative alpha-crystallin domain at the C-terminal part of the molecule

and retinoblastoma-like protein 2 (RBL2

The encoded protein is localized to the cytosol and mitochondria| and associates with membranes through an isoprenyl modification near the C-terminus

as indicated for members 1-3

LOXL4 Rabbit Polyclonal Antibody, 100ul Cell Culture Two transcript variants that encodeThis gene encodes a member of the lysyl oxidase gene family. The prototypic member of the family is essential to the biogenesis of connective tissue encoding an extracellular copper dependent amine oxidase that catalyses the first step in the formation of crosslinks in collagens and elastin. A highly conserved amino acid sequence at the C terminus end appears to be sufficient for amine oxidase activity suggesting that each family member may retain