Oct-1 Polyclonal Antibody, 50ul[BT-AP06328] DNA Fragments INPP5D is a member of

INPP5D is a member of the inositol polyphosphate-5-phosphatase (INPP5) family and encodes inositol polyphosphate-5-phosphatase D with an N-terminal SH2 domain

|disease:Individuals with systemic lupus erythematosus (SLE) and related disorders produce extremely large amounts of autoantibodies to p70 and p86

The encoded protein consists of four N-terminal immunoglobulin-like domains| six fibronectin type III domains| a transmembrane domain and a C-terminal internal domain that shares homology with the tumor suppressor candidate gene DCC

The encoded protein is found in a centrosomal complex with FEZ1

The encoded protein mediates the physiological effects of progesterone| which plays a central role in reproductive events associated with the establishment and maintenance of pregnancy

Oct-1 Polyclonal Antibody, 50ul[BT-AP06328] DNA Fragments INPP5D is a member ofThe OCT1 transcription factor was among the first identified members of the POU transcription factor family (summarized by Sturm et al. 1993 [PubMed 8314572]). Members of this family contain the POU domain, a 160 amino acid region necessary for DNA binding to the octameric sequence ATGCAAAT.