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PDZK3 Polyclonal Antibody, 100ul Live Cell Imaging This protein is functionally coupled

SKU: 81149039063

4.8
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PDZK3 Polyclonal Antibody, 100ul Live Cell Imaging This protein is functionally coupledThe PDZ domain containing 2 encoded by PDZD2 contains six PDZ domains and shares sequence similarity with pro interleukin 16 (pro IL 16). Like pro IL 16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

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Description

This protein is functionally coupled to adenylyl cyclase

Two transcript variants encoding the same protein have been found for APOL2

also named as TEM6

Mutations in this gene that result in enzymatic deficiency lead to the autosomal recessive disease mucopolysaccharidosis type I (MPS I)

which use CCR5 as a coreceptor

PDZK3 Polyclonal Antibody, 100ul Live Cell Imaging This protein is functionally coupledThe PDZ domain containing 2 encoded by PDZD2 contains six PDZ domains and shares sequence similarity with pro interleukin 16 (pro IL 16). Like pro IL 16, the encoded protein localizes to the endoplasmic reticulum and is thought to be cleaved by a caspase to produce a secreted peptide containing two PDZ domains. In addition, this gene is upregulated in primary prostate tumors and may be involved in the early stages of prostate tumorigenesis.

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