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Dok-2 Polyclonal Antibody, 20ul[BT-AP02698] Culture Plate Inserts The activity of the protein

SKU: 81569387888

4.6
PLN111.00 PLN149.00

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Dok-2 Polyclonal Antibody, 20ul[BT-AP02698] Culture Plate Inserts The activity of the proteinThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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Description

The activity of the protein (ABL proto-oncogene 1

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initiates survival pathways and cell proliferation

Dok-2 Polyclonal Antibody, 20ul[BT-AP02698] Culture Plate Inserts The activity of the proteinThe protein encoded by DOK2 (docking protein 2)is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210 (bcr abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.

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