GAAP Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) Multiple transcript variants encoding proteins

Multiple transcript variants encoding proteins with distinct C-terminal sequences have been described

disease:A chromosomal aberration involving FOXO4 is found in acute leukemias

The encoded protein interacts with cyclin-dependent kinase 8 and induces the phophorylation of the carboxy-terminal domain of the large subunit of RNA polymerase II

LTB is an inducer of the inflammatory response system and involved in normal development of lymphoid tissue

Mutations in this gene result in Dystonia 3

GAAP Polyclonal Antibody, 100ul Centrifuge Tube (Bottle) Multiple transcript variants encoding proteinsTMBIM4 (Transmembrane BAX Inhibitor Motif Containing 4) is a Protein Coding gene. Diseases associated with TMBIM4 include lassa fever and venezuelan hemorrhagic fever. An important paralog of this gene is FAIM2. Anti apoptotic protein which can inhibit apoptosis induced by intrinsic and extrinsic apoptotic stimuli. Can modulate both capacitative Ca2+ entry and inositol 1,4,5 trisphosphate (IP3) mediated Ca2+ release.