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SgK288 Polyclonal Antibody, 100ul Organelle Studies This type I membrane protein

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SgK288 Polyclonal Antibody, 100ul Organelle Studies This type I membrane proteinAnkyrin repeat and protein kinase domain containing protein 1 encoded by ANKK1 belongs to the Ser Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID: 1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of

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Description

This type I membrane protein mediates leukocyte-endothelial cell adhesion and signal transduction| and may play a role in the development of artherosclerosis and rheumatoid arthritis

Mutations in this gene have been associated with thrombophilia due to protein C deficiency| neonatal purpura fulminans| and recurrent venous thrombosis

and the regulation of IgE production

The proprotein is further cleaved into a fully processed form that can bind and activate VEGFR-2 and VEGFR-3 receptors

and the C-terminal segment of this domain is characterized by ten conserved cysteine residues

SgK288 Polyclonal Antibody, 100ul Organelle Studies This type I membrane proteinAnkyrin repeat and protein kinase domain containing protein 1 encoded by ANKK1 belongs to the Ser Thr protein kinase family, and protein kinase superfamily involved in signal transduction pathways. This gene is closely linked to DRD2 gene (GeneID: 1813) on chr 11, and a well studied restriction fragment length polymorphism (RFLP) designated TaqIA, was originally associated with the DRD2 gene, however, later was determined to be located in exon 8 of

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