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RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator The 3-phosphoinositide dependent protein kinase-1

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RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator The 3-phosphoinositide dependent protein kinase-1RFC1 encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have

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Description

The 3-phosphoinositide dependent protein kinase-1 (PDPK1/PDK1) is reported to phosphorylate this kinase| which may mediate insulin signals to the actin cytoskeleton

This gene encodes a protein that is one of the two components of elastic fibers

Defects in this gene are the cause of hypomagnesemia type 4

It binds to the TGACCT repeat motif enhancing the renin gene and thus acting as a negative modulator of renin gene transcription

The genes for the beta chains of chorionic gonadotropin and for luteinizing hormone are contiguous on chromosome 19q13

RFC1 Polyclonal Antibody, 50ul[BT-AP07768] Vacuum Aspirator The 3-phosphoinositide dependent protein kinase-1RFC1 encodes the large subunit of replication factor C, a five subunit DNA polymerase accessory protein, which is a DNA dependent ATPase required for eukaryotic DNA replication and repair. The large subunit acts as an activator of DNA polymerases, binds to the 3' end of primers, and promotes coordinated synthesis of both strands. It may also have a role in telomere stability. Alternatively spliced transcript variants encoding different isoforms have

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