NM23-H1 Monoclonal Antibody, 50ul ssDNA Synthesis Dok-2 and Dok-3 are members

Dok-2 and Dok-3 are members of a class of "docking" proteins which contain multiple tyrosine residues and putative SH2 binding sites

stabilizing ligand binding and enhancing kinase-mediated activation of downstream signalling pathways

and share DNA-binding

Three alternatively spliced transcript variants encoding distinct isoforms have been reported

carcinogenic

NM23-H1 Monoclonal Antibody, 50ul ssDNA Synthesis Dok-2 and Dok-3 are membersThis gene (NME1) was identified because of its reduced mRNA transcript levels in highly metastatic cells. Nucleoside diphosphate kinase (NDK) exists as a hexamer composed of 'A' (encoded by this gene) and 'B' (encoded by NME2) isoforms. Mutations in this gene have been identified in aggressive neuroblastomas. Two transcript variants encoding different isoforms have been found for this gene. Co transcription of this gene and the neighboring downstream